CD80 Antikörper (FITC)

Produktnummer ABIN6655081

Hersteller Produkt- Nr.: 200-302-n74

Der Maus Monoklonal Anti-CD80-Antikörper wurde für FACS, WB und IHC validiert. Er ist geeignet, CD80 in Proben von Human zu detektieren.

Kurzübersicht für CD80 Antikörper (FITC) (ABIN6655081)

Target: CD80

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD80 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 2D10

Produktdetails anti-CD80 Antikörper (FITC)

Hersteller Produkt- Nr.: 200-302-n74

Hersteller: Rockland

Verwendungszweck: CD80 Fluorescein Antibody

Kreuzreaktivität (Details): Reactivity is observed against human CD80.

Aufreinigung: Fluorescein conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD80.

Sterilität: Sterile filtered

Immunogen: Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen.

Isotyp: IgG1 kappa

Labeling Ratio: 4-6

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: User Optimized

Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells

Western_Blot_Dilution: User Optimized

Kommentare:

Anti-CD80 is tested for Flow Cytometry and is useful for Immunohistochemistry and Western Blot. Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Haltbarkeit: 6 months

Details zu CD80

Target: CD80

Andere Bezeichnung: CD80

Hintergrund:

Synonyms: T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD28LG, CD28LG1, LAB7

Background: CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.

Gene Name: CD80

Gen-ID: 941

NCBI Accession: NP_005182

UniProt: P33681

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints