IL7R Antikörper (AA 21-236)
Kurzübersicht für IL7R Antikörper (AA 21-236) (ABIN6654530)
Target
Alle IL7R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 21-236
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Verwendungszweck
- CD127 Antibody / IL7R
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.
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Isotyp
- IgG2c, kappa
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Applikationshinweise
- Optimal dilution of the CD127 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the CD127 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IL7R (Interleukin 7 Receptor (IL7R))
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Andere Bezeichnung
- CD127
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Hintergrund
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
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UniProt
- P16871
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Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
Target
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