ADRP Antikörper

Produktnummer ABIN6654241

Der Kaninchen Monoklonal Anti-ADRP-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, ADRP in Proben von Human zu detektieren.

Kurzübersicht für ADRP Antikörper (ABIN6654241)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ADRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ADFP-2755R

Produktdetails anti-ADRP Antikörper

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: A portion of amin acids 249-376 from the human protein were used as the immunogen for this recombinant Adipophilin antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant Adipophilin antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. ELISA: order formulation without BSA for coating,Immunohistochemistry (FFPE): 1-2 μg/mL,Prediluted IHC only format: incubate for 30 min at RT (1),Western blot: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The recombinant Adipophilin antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Andere Bezeichnung: Adipophilin / Perilipin 2 / ADRP / PLIN2

Hintergrund: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism