CD2AP Antikörper (AA 253-337)

Produktnummer ABIN6654151

Der Maus Monoklonal Anti-CD2AP-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, CD2AP in Proben von Human zu detektieren.

Kurzübersicht für CD2AP Antikörper (AA 253-337) (ABIN6654151)

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 5F8

Produktdetails anti-CD2AP Antikörper

Bindungsspezifität: AA 253-337

Aufreinigung: Protein G affinity

Immunogen: Amino acids K253-K337 from the human protein were used as the immunogen for the CD2AP antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD2AP antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CD2AP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Andere Bezeichnung: CD2AP

Hintergrund: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

UniProt: Q9Y5K6