DKK1 Antikörper (AA 32-266)

Produktnummer ABIN6654082

Der Kaninchen Polyklonal Anti-DKK1-Antikörper wurde für WB und ELISA (Capture) validiert. Er ist geeignet, DKK1 in Proben von Human zu detektieren.

Kurzübersicht für DKK1 Antikörper (AA 32-266) (ABIN6654082)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Produktdetails anti-DKK1 Antikörper

Bindungsspezifität: AA 32-266

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids T32-H266 from the human protein were used as the immunogen for the DKK1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DKK1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the DKK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1

Hintergrund: DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

UniProt: O94907

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation