Betacellulin Antikörper (AA 32-111)

Produktnummer ABIN6654020

Dieses Anti-Betacellulin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Betacellulin in WB, IHC (p) und ELISA (Capture). Geeignet für Human.

Kurzübersicht für Betacellulin Antikörper (AA 32-111) (ABIN6654020)

Target: Betacellulin (BTC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Betacellulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Produktdetails anti-Betacellulin Antikörper

Bindungsspezifität: AA 32-111

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids D32-Y111 from the human protein were used as the immunogen for the BTC antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the BTC antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the BTC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Betacellulin

Target: Betacellulin (BTC)

Andere Bezeichnung: BTC / Betacellulin

Hintergrund: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

UniProt: P35070

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung