MAP4K3 Antikörper

Produktnummer ABIN659123

Der Maus Monoklonal Anti-MAP4K3-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, MAP4K3 in Proben von Human zu detektieren.

Kurzübersicht für MAP4K3 Antikörper (ABIN659123)

Target: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP4K3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 219CT8-3-1

Produktdetails anti-MAP4K3 Antikörper

Aufreinigung: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This MAP4K3 monoclonal antibody is generated from mouse immunized with MAP4K3 recombinant protein.

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:100~500. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: MAP4K3 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu MAP4K3

Target: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Andere Bezeichnung: MAP4K3

Hintergrund: This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

Molekulargewicht: 101316

Gen-ID: 8491

NCBI Accession: NP_001257354, NP_003609

UniProt: Q8IVH8

Pathways: MAPK Signalweg