LIM Domain Kinase 1 Antikörper (C-Term)
Kurzübersicht für LIM Domain Kinase 1 Antikörper (C-Term) (ABIN659052)
Target
Alle LIM Domain Kinase 1 (LIMK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 479-508, C-Term
-
Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
Immunogen
- This LIMK1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human LIMK1.
-
Isotyp
- IgM kappa
-
-
-
-
Applikationshinweise
- WB: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Haltbarkeit
- 6 months
-
-
- LIM Domain Kinase 1 (LIMK1)
-
Andere Bezeichnung
- LIMK1
-
Hintergrund
- Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
-
Molekulargewicht
- 72585
-
Gen-ID
- 3984
-
NCBI Accession
- NP_001191355, NP_002305
-
UniProt
- P53667
-
Pathways
- Caspase Kaskade in der Apoptose, Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
-