TUBA1A Antikörper (acLys40)

Produktnummer ABIN6579750

Der Kaninchen Polyklonal anti-TUBA1A Antikörper wird verwendet zum Nachweis von TUBA1A in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für TUBA1A Antikörper (acLys40) (ABIN6579750)

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBA1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TUBA1A Antikörper

Bindungsspezifität: AA 1-50, acLys40

Verwendungszweck: Tubulin α (Acetyl Lys40) Antibody

Spezifität: Acetyl-Tubulin α (K40) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K40.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human TUBA1A around the Acetylation site of Lys40. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TUBA1A

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Andere Bezeichnung: TUBA1A

Hintergrund:

Synonyms: TUBA1A, TUBA3, Tubulin alpha-1A chain, Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain, TUBA1B, Tubulin alpha-1B chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain, TUBA1C, TUBA6, Tubulin alpha-6 chain, TUBA3C, TUBA2, TUBA3D, Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, TUBA4A, TUBA1, Tubulin alpha-4A chain, Alpha-tubulin 1, Testis-specific alpha-tubulin,

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Gene Name: TUBA1A/TUBA1B/TUBA1C/TUBA3C/TUBA4A

Protein Name: Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain/Tubulin alpha-3C/D chain/Tubulin alpha-4A chain

Molekulargewicht: 50 kDa

Gen-ID: 7846, 10376, 84790

OMIM: 602529

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase