Amphiregulin Antikörper (AA 91-140)

Produktnummer ABIN6579595

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Amphiregulin in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Amphiregulin Antikörper (AA 91-140) (ABIN6579595)

Target: Amphiregulin (AREG)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amphiregulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Amphiregulin Antikörper

Bindungsspezifität: AA 91-140

Verwendungszweck: Amphiregulin Antibody

Spezifität: Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Amphiregulin

Target: Amphiregulin (AREG)

Andere Bezeichnung: AREG/AREGB

Hintergrund:

Synonyms: AREG, SDGF, AREGB, Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF

Background: The protein encoded byThis gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],

Gene Name: AREG/AREGB

Protein Name: Amphiregulin

Molekulargewicht: 27 kDa

Gen-ID: 374, 727738

OMIM: 104640

UniProt: P15514

Pathways: RTK Signalweg, EGFR Signaling Pathway