CD226 Antikörper (AA 71-120)

Produktnummer ABIN6579545

Der Kaninchen Polyklonal anti-CD226 Antikörper (ABIN6579545) detektiert spezifisch CD226 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CD226 Antikörper (AA 71-120) (ABIN6579545)

Target: CD226

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD226 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD226 Antikörper

Bindungsspezifität: AA 71-120

Verwendungszweck: DNAM-1 Antibody

Spezifität: DNAM-1 Polyclonal Antibody detects endogenous levels of DNAM-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CD226

Target: CD226

Andere Bezeichnung: CD226

Hintergrund:

Synonyms: CD226, DNAM1, CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226

Background: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: CD226

Protein Name: CD226 antigen

Molekulargewicht: 38-65 kDa

Gen-ID: 10666

OMIM: 605397

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints