CR1L Antikörper (AA 300-350)

Produktnummer ABIN6579446

Der Kaninchen Polyklonal anti-CR1L Antikörper wird verwendet zum Nachweis von CR1L in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für CR1L Antikörper (AA 300-350) (ABIN6579446)

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CR1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CR1L Antikörper

Bindungsspezifität: AA 300-350

Verwendungszweck: CD35 Antibody

Spezifität: CD35 Polyclonal Antibody detects endogenous levels of CD35

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CR1/CR1L. AA range:300-350 & 740-790

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000, ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CR1L

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Andere Bezeichnung: CR1/CR1L

Hintergrund:

Synonyms: complement component (3b/4b) receptor 1/2 (Knops blood group)

Background: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants

Protein Name: CD35

Molekulargewicht: '220 kDa

Gen-ID: 1378, 1379

UniProt: P17927

Pathways: Komplementsystem