CD3D Antikörper (AA 41-90)

Produktnummer ABIN6579432

Der Kaninchen Polyklonal anti-CD3D Antikörper wird verwendet zum Nachweis von CD3D in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für CD3D Antikörper (AA 41-90) (ABIN6579432)

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-CD3D Antikörper

Bindungsspezifität: AA 41-90

Verwendungszweck: CD3-δ Antibody

Spezifität: CD3-δ Polyclonal Antibody detects endogenous levels of CD3-δ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD3D. AA range:41-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CD3D

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Andere Bezeichnung: CD3D

Hintergrund:

Synonyms: CD3D, T3D, T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain, CD3d

Background: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009],

Gene Name: CD3D

Protein Name: T-cell surface glycoprotein CD3 delta chain

Molekulargewicht: 18 kDa

Gen-ID: 915

OMIM: 186790

UniProt: P04234

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events