FGF8 Antikörper (AA 141-190)

Produktnummer ABIN6579254

Der Kaninchen Polyklonal anti-FGF8 Antikörper wird verwendet zum Nachweis von FGF8 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für FGF8 Antikörper (AA 141-190) (ABIN6579254)

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FGF8 Antikörper

Bindungsspezifität: AA 141-190

Verwendungszweck: FGF-8 Antibody

Spezifität: FGF-8 Polyclonal Antibody detects endogenous levels of FGF-8 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FGF8. AA range:141-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FGF8

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Andere Bezeichnung: FGF8

Hintergrund:

Synonyms: FGF8, AIGF, Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8

Background: The protein encoded byThis gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene re

Gene Name: FGF8

Protein Name: Fibroblast growth factor 8

Molekulargewicht: 26 kDa

Gen-ID: 2253

OMIM: 600483

UniProt: P55075

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis