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Nemo-Like Kinase Antikörper (C-Term)

NLK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34651 unconjugated
Produktnummer ABIN657850
  • Target Alle Nemo-Like Kinase (NLK) Antikörper anzeigen
    Nemo-Like Kinase (NLK)
    Bindungsspezifität
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reaktivität
    • 80
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 81
    • 4
    Kaninchen
    Klonalität
    • 83
    • 2
    Polyklonal
    Konjugat
    • 25
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nemo-Like Kinase Antikörper ist unkonjugiert
    Applikation
    • 77
    • 41
    • 26
    • 26
    • 23
    • 16
    • 13
    • 10
    • 10
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
    Klon
    RB34651
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NLK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    Nemo-Like Kinase (NLK)
    Andere Bezeichnung
    Nlk (NLK Produkte)
    Synonyme
    Amf antikoerper, Gpi1 antikoerper, AI194375 antikoerper, nlk antikoerper, nlkb antikoerper, zgc:111875 antikoerper, Xnlk antikoerper, nlk1 antikoerper, nlk2 antikoerper, NLK antikoerper, nemo-like antikoerper, RGD1561602 antikoerper, glucose-6-phosphate isomerase antikoerper, nemo like kinase antikoerper, nemo-like kinase, type 1 antikoerper, nemo-like kinase L homeolog antikoerper, Nemo-Like kinase antikoerper, nemo-like kinase antikoerper, Gpi antikoerper, NLK antikoerper, Nlk antikoerper, nlk1 antikoerper, nlk.L antikoerper, nlk antikoerper, nemo-like antikoerper
    Hintergrund
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
    Molekulargewicht
    58313
    Gen-ID
    100044468, 18099
    NCBI Accession
    NP_032728
    UniProt
    O54949
    Pathways
    Ubiquitin Proteasome Pathway
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