MDM4-binding Protein Antikörper (AA 128-157)

Produktnummer ABIN657782

Der Kaninchen Polyklonal Anti-MDM4-binding Protein-Antikörper wurde für WB validiert. Er ist geeignet, MDM4-binding Protein in Proben von Human zu detektieren.

Kurzübersicht für MDM4-binding Protein Antikörper (AA 128-157) (ABIN657782)

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDM4-binding Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33903

Produktdetails anti-MDM4-binding Protein Antikörper

Bindungsspezifität: AA 128-157

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human MDM4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: MDM4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu MDM4-binding Protein

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Andere Bezeichnung: MDM4

Hintergrund: The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.

Molekulargewicht: 54864

Gen-ID: 4194

NCBI Accession: NP_001191100, NP_001191101, NP_001265445, NP_001265446, NP_001265447, NP_001265448, NP_002384

UniProt: O15151

Pathways: Zellzyklus