POF1B Antikörper (AA 337-366)

Produktnummer ABIN657749

Der Kaninchen Polyklonal Anti-POF1B-Antikörper wurde für WB validiert. Er ist geeignet, POF1B in Proben von Maus zu detektieren.

Kurzübersicht für POF1B Antikörper (AA 337-366) (ABIN657749)

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33064

Produktdetails anti-POF1B Antikörper

Bindungsspezifität: AA 337-366

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: POF1B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu POF1B

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Andere Bezeichnung: POF1B

Hintergrund: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.

Molekulargewicht: 68065

Gen-ID: 79983

NCBI Accession: NP_079197

UniProt: Q8WVV4