POF1B Antikörper (AA 330-560)
Kurzübersicht für POF1B Antikörper (AA 330-560) (ABIN7269509)
Target
Alle POF1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 330-560
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Verwendungszweck
- POF1B Rabbit pAb
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Sequenz
- LVLSTFSNIR EELGHLQNDM TSLENDKMRL EKDLSFKDTQ LKEYEELLAS VRANNHQQQQ GLQDSSSKCQ ALEENNLSLR HTLSDMEYRL KELEYCKRNL EQENQNLRMQ VSETCTGPML QAKMDEIGNH YTEMVKNLRM EKDREICRLR SQLNQYHKDV SKREGSCSDF QFKLHELTSL LEEKDSLIKR QSEELSKLRQ EIYSSHNQPS TGGRTTITTK KYRTQYPILG L
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- POF1B (Premature Ovarian Failure, 1B (POF1B))
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Andere Bezeichnung
- POF1B
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Hintergrund
- Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010],POF;POF2B;POF1B,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Microfilaments,POF1B
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Gen-ID
- 79983
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UniProt
- Q8WVV4
Target
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