CD33 Antikörper (AA 88-117)

Produktnummer ABIN657464

Der Kaninchen Polyklonal Anti-CD33-Antikörper wurde für WB validiert. Er ist geeignet, CD33 in Proben von Human zu detektieren.

Kurzübersicht für CD33 Antikörper (AA 88-117) (ABIN657464)

Target: CD33

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33637

Produktdetails anti-CD33 Antikörper

Bindungsspezifität: AA 88-117

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human CD33.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CD33 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu CD33

Target: CD33

Andere Bezeichnung: CD33

Hintergrund: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Molekulargewicht: 39825

Gen-ID: 945

NCBI Accession: NP_001076087, NP_001171079, NP_001763

UniProt: P20138