LIG1 Antikörper (AA 1-919)

Produktnummer ABIN190291

Dieser Maus Monoklonal Antikörper detektiert spezifisch LIG1 in WB, IP, IHC (p) und IF/ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LIG1 Antikörper (AA 1-919) (ABIN190291)

Target: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LIG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)

Klon: 10H5

Produktdetails anti-LIG1 Antikörper

Bindungsspezifität: AA 1-919

Verwendungszweck: Anti-DNA Ligase I Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human DNA Ligase I (125 kD), one of the four ligase proteins found in mammalian cells that are required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.

Kreuzreaktivität: Human

Immunogen: Recombinant human DNA Ligase I (aa 1-919) purified from baculovirus infected Sf9 cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-5 μg/mL.
Immunoprecipitation: use at 1-5 μg/mL.
Positive controls: MCF-7 cells or recombinant protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4

Lagerung: -80 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.

Details zu LIG1

Target: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Andere Bezeichnung: DNA ligase 1

Hintergrund: DNA ligase 1,DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.,Nucleus.,EC 6.5.1.1, DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1

UniProt: P18858

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA