KIR3DS1 Antikörper (Killer Cell Immunoglobulin-Like Receptor, three Domains, Short Cytoplasmic Tail, 1)

Details for Product anti-KIR3DS1 Antibody No. ABIN6572080
Antigen
  • CD158E2
  • KIR-123FM
  • KIR-G1
  • NKAT10
  • killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
  • killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
  • KIR3DS1
Reaktivität
Human, Maus, Ratte (Rattus)
24
4
4
Wirt
Kaninchen
24
Klonalität
Polyklonal
Konjugat
Dieser KIR3DS1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
24
14
1
1
1
Optionen
Immunogen Recombinant protein of human KIR3DS1
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere KIR3DS1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung KIR3DS1
Hintergrund

Synonyms: Killer Cell Immunoglobulin Like Receptor Three Ig Domains And Short Cytoplasmic Tail 1,Killer Cell Immunoglobulin-Like Receptor Three Domains, Short Cytoplasmic Tail 1,Natural Killer-Associated Transcript 10,NKAT-10,NKAT10,Killer Cell Immunoglobulin-Like Receptor KIR3DS1,Killer Cell Immunoglobulin-Like Receptor 3DS1,MHC Class I NK Cell Receptor,KIR-123FM,CD158E2,KIR-G1

Background: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 60kDa

Calculated_MW: 42kDa

Gen-ID 3813
UniProt Q14943
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Killer Cell Immunoglobulin-Like Receptor, three Domains, Short Cytoplasmic Tail, 1 (KIR3DS1) antibody (ABIN6572080) Western blot analysis of extracts of various cell lines, using KIR3DS1 antibody.
Haben Sie etwas anderes gesucht?