Nodal Antikörper

Produktnummer ABIN6572072

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Nodal in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für Nodal Antikörper (ABIN6572072)

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nodal Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Nodal Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NODAL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Nodal

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Andere Bezeichnung: NODAL

Hintergrund:

Synonyms: HTX5,MGC138230,Nodal,Nodal Growth Differentiation Factor,nodal homolog (mouse),Nodal homolog,Nodal,Mouse,Homolog,NODAL

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Molekulargewicht:

Observed_MW: 44kDa

Calculated_MW: 39kDa

Gen-ID: 4838

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity