Synonyms: Leukocyte L1 complex heavy chain,60B8AG,CAGB,Calgranulin B,Calgranulin-B,Calprotectin L1H subunit,CFAG,CGLB,Cystic fibrosis antigen B,L1AG,Leukocyte L1 complex heavy chain,LIAG,MAC387,MIF,Migration inhibitory factor related protein 14,Migration inhibitory factor-related protein 14,MRP 14,MRP-14,MRP14,Myeloid-related protein 14,NIF,OTTHUMP00000015331,p14,Protein S100-A9,S100 A9,S100 calcium binding protein A9,S100 calcium binding protein A9 calgranulin B,S100 calcium-binding protein A9,S100A9,S10A9
Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity.