Synonyms: 8430421I07Rik,AI047774,Deubiquitinating enzyme 19,Ubiquitin carboxyl terminal hydrolase 19,Ubiquitin carboxyl-terminal hydrolase 19,Ubiquitin specific peptidase 19,Ubiquitin specific processing protease 19,Ubiquitin specific protease 19,Ubiquitin thioesterase 19,Ubiquitin thiolesterase 19,Ubiquitin-specific-processing protease 19,UBP19,Usp19,Zinc finger MYND domain containing protein 9,Zinc finger MYND domain-containing protein 9,ZMYND9
Background: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.