YBX1 Antikörper

Produktnummer ABIN6571294

Der Kaninchen Polyklonal anti-YBX1 Antikörper (ABIN6571294) detektiert spezifisch YBX1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für YBX1 Antikörper (ABIN6571294)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-YBX1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human YBX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Andere Bezeichnung: YBX1

Hintergrund:

Synonyms: BP 8,CBF-A,CCAAT binding transcription factor I subunit A,CCAAT-binding transcription factor I subunit A,CSDA2,CSDB,DBPB,DNA binding protein B,DNA-binding protein B,EFI-A,Enhancer factor I subunit A,MDR NF1,MGC104858,MGC110976,MGC117250,NSEP 1,NSEP1,Nuclease sensitive element binding protein 1,Nuclease-sensitive element-binding protein 1,p50,Q15905,Y-box binding protein 1,Y-box transcription factor,Y-box-binding protein 1,YB 1,YB-1,YBOX1,YBX 1,ybx1

Background: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Molekulargewicht:

Observed_MW: 50kDa

Calculated_MW: 35kDa

Gen-ID: 4904

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation