ITGA2 Antikörper

Produktnummer ABIN5968272

Der Kaninchen Polyklonal Anti-ITGA2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ITGA2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ITGA2 Antikörper (ABIN5968272)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ITGA2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ITGA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: ITGA2

Hintergrund:

Synonyms: BR,CD 49b,CD49 antigen like family member B,CD49 antigen-like family member B,CD49b,CD49b antigen,Collagen receptor,DX5,Glycoprotein Ia deficiency included,GP Ia,GP Ia deficiency,included,GPIa,HPA 5 included,HPA5 included,Human platelet alloantigen system 5,Integrin alpha 2,Integrin alpha II,Integrin alpha-2,Integrin,alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor),ITA2,ITGA2,Platelet alloantigen Br(a),included,Platelet antigen Br,Platelet glycoprotein GPIa,Platelet glycoprotein Ia,Platelet glycoprotein Ia/IIa,Platelet membrane glycoprotein Ia,Platelet receptor for collagen,deficiency of,included,Very late activation protein 2 receptor alpha 2 subunit,VLA 2 alpha chain,VLA 2,VLA 2 subunit alpha,VLA-2 subunit alpha,VLA2,VLA2 receptor alpha 2 subunit,VLAA2

Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 150kDa

Calculated_MW: 129kDa

Gen-ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex