WISP2 Antikörper

Produktnummer ABIN6571151

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WISP2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für WISP2 Antikörper (ABIN6571151)

Target: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WISP2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human WISP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WISP2

Target: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Andere Bezeichnung: WISP2

Hintergrund:

Synonyms: CCN family member 5,CCN5,Connective tissue growth factor like protein,Connective tissue growth factor related protein 58,Connective tissue growth factor-like protein,Connective tissue growth factor-related protein 58,CT58,CTGF L,CTGF-L,WISP 2,WISP-2,Wisp2,WISP2,Wnt 1 signaling pathway protein 2,WNT1 inducible signaling pathway protein 2,WNT1-inducible-signaling pathway protein 2

Background: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Molekulargewicht:

Observed_MW: 27kDa

Calculated_MW: 22kDa/26kDa

Gen-ID: 8839

UniProt: O76076

Pathways: WNT Signalweg, Growth Factor Binding