RASSF5 Antikörper

Produktnummer ABIN6571110

Der Kaninchen-Polyklonal Anti-RASSF5-Antikörper wurde für WB und IHC validiert. Er ist geeignet zum Nachweis von RASSF5 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für RASSF5 Antikörper (ABIN6571110)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RASSF5 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RASSF5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Andere Bezeichnung: RASSF5

Hintergrund:

Synonyms: Maxp 1,MAXP1,MGC10823,MGC17344,New ras effector 1,NORE 1,NORE1A,NORE1B,Novel Ras effector 1,RAP1 Binding Protein,RAPL,Ras association (RalGDS/AF 6) domain family 5,Ras association (RalGDS/AF 6) domain family member 5,Ras association domain containing family protein 5,Ras association domain-containing protein 5,Ras effector like protein,RASF5,RASSF 3,RASSF 5,RASSF3,RASSF5,Regulator for cell adhesion and polarization enriched in lymphoid tissue ,Regulator for cell adhesion and polarization enriched in lymphoid tissues,Tumor suppressor RASSF3

Background: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 37kDa, 45kDa

Calculated_MW: 30kDa/37kDa/47kDa

Gen-ID: 83593

UniProt: Q8WWW0

Pathways: T-Zell Rezeptor Signalweg