FUBP1 Antikörper

Produktnummer ABIN6569996

Produktdetails anti-FUBP1 Antikörper

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUBP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human FUBP1 (NP_003893.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FUBP1

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Andere Bezeichnung: FUBP1 (FUBP1 Produkte)

Synonyme: FBP antikoerper, FUBP antikoerper, fbp antikoerper, fubp antikoerper, MGC53183 antikoerper, MGC75632 antikoerper, FUBP1 antikoerper, DKFZp468N0812 antikoerper, 9530027K12Rik antikoerper, D3Ertd330e antikoerper, Fubp antikoerper, Fubp4 antikoerper, MGC78835 antikoerper, wu:fa92h11 antikoerper, wu:fb24h11 antikoerper, wu:fc26f06 antikoerper, zgc:66046 antikoerper, far upstream element binding protein 1 antikoerper, far upstream element (FUSE) binding protein 1 S homeolog antikoerper, far upstream element (FUSE) binding protein 1 antikoerper, far upstream element binding protein 1 L homeolog antikoerper, FUBP1 antikoerper, fubp1.S antikoerper, fubp1 antikoerper, Fubp1 antikoerper, fubp1.L antikoerper

Hintergrund: The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 79kDa

Calculated_MW: 67kDa/68kDa

Gen-ID: 8880

UniProt: Q96AE4