REST Antikörper (RE1-Silencing Transcription Factor)

Details for Product anti-REST Antibody No. ABIN6569191
Target
Reaktivität
Human
52
9
9
3
3
3
3
3
2
1
1
1
Wirt
Kaninchen
49
2
1
Klonalität
Polyklonal
Konjugat
Dieser REST Antikörper ist unkonjugiert
5
4
3
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF)
40
23
8
6
5
5
2
1
1
1
Optionen
Immunogen A synthetic Peptide of human REST
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung REST (REST Antibody Abstract)
Hintergrund

Synonyms: Neural Restrictive Silencer Factor,Neural-restrictive silencer factor,Neuron Restrictive Silencer Factor,NRSF,RE1 silencing transcription factor,RE1-silencing transcription factor,Repressor binding to the X2 box,rest,REST protein,REST,X2 box repressor,XBR

Background: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described

Molekulargewicht

Calculated_MW: 35kDa/36kDa/119kDa/121kDa

Gen-ID 5978
UniProt Q13127
Pathways Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
Applikations-hinweise IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-RE1-Silencing Transcription Factor (REST) antibody (ABIN6569191) Immunofluorescence analysis of MCF-7 cells using REST antibody.