PLAU Antikörper

Produktnummer ABIN6569163

Der Kaninchen Polyklonal anti-PLAU Antikörper (ABIN6569163) detektiert spezifisch PLAU in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PLAU Antikörper (ABIN6569163)

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAU Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PLAU Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PLAU

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PLAU

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Andere Bezeichnung: PLAU

Hintergrund:

Synonyms: ATF,ATF uPA,BDPLT5,Plasminogen activator,Plasminogen activator urinary,Plasminogen activator urokinase,PLAU,QPD,u PA,U plasminogen activator,u-PA,U-plasminogen activator,uPA,URK,UROK,Urokinase plasminogen activator,Urokinase type plasminogen activator,Urokinase type plasminogen activator precursor,Urokinase-type plasminogen activator chain B

Background: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht:

Observed_MW: 45kDa

Calculated_MW: 46kDa/48kDa

Gen-ID: 5328

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration