Histone Deacetylase 2 (HDAC2) Antikörper

Details zu Produkt Nr. ABIN6569092
Target
Reaktivität
Human, Affe, Maus, Ratte
149
98
89
14
8
6
6
4
4
4
4
2
1
1
1
1
1
Wirt
Kaninchen
131
17
3
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
8
6
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
111
54
51
40
31
26
25
18
13
6
5
3
3
3
2
2
1
1
Optionen
Immunogen A synthetic peptide of human HDAC2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung HDAC2 (HDAC2 Antibody Abstract)
Hintergrund

Synonyms: D10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp

Background: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 56kDa

Calculated_MW: 51kDa/55kDa

Gen-ID 3066
UniProt Q92769
Pathways Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Histone Deacetylase 2 (HDAC2) antibody (ABIN6569092) Western blot analysis of extracts of various cell lines, using HDAC2 antibody.
Image no. 2 for anti-Histone Deacetylase 2 (HDAC2) antibody (ABIN6569092) Immunohistochemistry of paraffin-embedded rat kidney using HDAC2 antibody.
Image no. 3 for anti-Histone Deacetylase 2 (HDAC2) antibody (ABIN6569092) Immunoprecipitation analysis of 200ug extracts of K562 cells using 1ug HDAC2 antibody.
Image no. 4 for anti-Histone Deacetylase 2 (HDAC2) antibody (ABIN6569092) Immunofluorescence analysis of A549 cells using HDAC2 antibody.