Chitotriosidase 1 Antikörper (Chitotriosidase)

Details for Product anti-CHIT1 Antibody No. ABIN6569050
Target
Reaktivität
Human, Maus
40
4
2
Wirt
Kaninchen
25
12
7
Klonalität
Polyklonal
Konjugat
Dieser Chitotriosidase 1 Antikörper ist unkonjugiert
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
37
21
9
5
4
4
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human CHIT1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CHIT1 (CHIT1 Antibody Abstract)
Hintergrund

Synonyms: CHI3,CHIT,CHIT1,CHIT1,CHITD,Chitinase 1 ,Chitinase 1 (chitotriosidase),Chitinase-1,Chitotriosidase,Chitotriosidase-1,EC 3.2.1.14,FLJ00314,MGC125322,Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase

Background: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Molekulargewicht

Observed_MW: 52kDa

Calculated_MW: 43kDa/48kDa/49kDa/51kDa

Gen-ID 1118
UniProt Q13231
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Chitotriosidase (CHIT1) antibody (ABIN6569050) Western blot analysis of extracts of various cell lines, using CHIT1 antibody.
Image no. 2 for anti-Chitotriosidase (CHIT1) antibody (ABIN6569050) Immunohistochemistry of paraffin-embedded human normal stomach using CHIT1 antibody.