Chitotriosidase 1 Antikörper

Produktnummer ABIN6569050

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Chitotriosidase 1 in IHC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Chitotriosidase 1 Antikörper (ABIN6569050)

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Chitotriosidase 1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CHIT1 (NP_003456.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Chitotriosidase 1

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Andere Bezeichnung: CHIT1

Hintergrund: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Molekulargewicht:

Observed_MW: 52kDa

Calculated_MW: 43kDa/48kDa/49kDa/51kDa

Gen-ID: 1118

UniProt: Q13231