TMPRSS2 Antikörper (Transmembrane Protease, serine 2)

Details for Product anti-TMPRSS2 Antibody No. ABIN6569022
Target
Reaktivität
Human, Maus
50
27
19
1
1
1
Wirt
Kaninchen
40
7
5
Klonalität
Polyklonal
Konjugat
Dieser TMPRSS2 Antikörper ist unkonjugiert
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
38
18
13
8
4
3
3
2
2
1
Optionen
Immunogen Recombinant protein of human TMPRSS2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TMPRSS2 (TMPRSS2 Antibody Abstract)
Hintergrund

Synonyms: D16Ertd61e,Epitheliasin,FLJ41954,MGC6821,PP9284,PRSS10,Serine protease 10,TMPRSS2,TMPRSS2 ERG FUSION GENE,INCLUDED,TMPRSS2 ETV1 FUSION GENE,INCLUDED,TMPS2,Transmembrane protease serine 2 catalytic chain,Transmembrane protease,serine 2,Transmembrane protease,serine 2,EC 3.4.219

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 52kDa

Calculated_MW: 53kDa/57kDa

Gen-ID 7113
UniProt O15393
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Transmembrane Protease, serine 2 (TMPRSS2) antibody (ABIN6569022) Western blot analysis of extracts of 22Rv1 cells, using TMPRSS2 antibody.
Image no. 2 for anti-Transmembrane Protease, serine 2 (TMPRSS2) antibody (ABIN6569022) Immunohistochemistry of paraffin-embedded human stomach cancer using TMPRSS2 antibody.