TMPRSS2 Antikörper

Produktnummer ABIN6569022

Dieses Anti-TMPRSS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TMPRSS2 in WB und IHC. Geeignet für Human.

Kurzübersicht für TMPRSS2 Antikörper (ABIN6569022)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TMPRSS2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human TMPRSS2 (NP_001128571.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Andere Bezeichnung: TMPRSS2

Hintergrund: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 52kDa

Calculated_MW: 53kDa/57kDa

Gen-ID: 7113

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interaktom