TAPBP Antikörper (TAP Binding Protein (Tapasin))

Details for Product anti-TAPBP Antibody No. ABIN6569012
Target
Reaktivität
Human, Maus, Ratte
39
8
6
5
5
5
2
1
1
1
Wirt
Kaninchen
39
Klonalität
Polyklonal
Konjugat
Dieser TAPBP Antikörper ist unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
33
17
9
3
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human TAPBP
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TAPBP (TAPBP Antibody Abstract)
Hintergrund

Synonyms: NGS 17,NGS-17,NGS17,TAP associated protein ,TAP binding protein ,TAP binding protein (tapasin),TAP BP,TAP-associated protein,TAP-binding protein,TAPA,Tapasin,TAPBP,TPN,TPSN,TPSN

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Molekulargewicht

Observed_MW: 48kDa

Calculated_MW: 38kDa/43kDa/47kDa/53kDa

Gen-ID 6892
UniProt O15533
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-TAP Binding Protein (Tapasin) (TAPBP) antibody (ABIN6569012) Western blot analysis of extracts of HT-29 cells, using TAPBP antibody.
Image no. 2 for anti-TAP Binding Protein (Tapasin) (TAPBP) antibody (ABIN6569012) Immunohistochemistry of paraffin-embedded human stomach using TAPBP Antibody.
Image no. 3 for anti-TAP Binding Protein (Tapasin) (TAPBP) antibody (ABIN6569012) Immunohistochemistry of paraffin-embedded human gastric cancer using TAPBP Antibody.
Image no. 4 for anti-TAP Binding Protein (Tapasin) (TAPBP) antibody (ABIN6569012) Immunohistochemistry of paraffin-embedded mouse kidney using TAPBP Antibody.