U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Antikörper

Details zu Produkt Nr. ABIN6568989
Target
Reaktivität
Human, Maus
45
19
18
6
6
5
5
4
2
2
2
1
1
1
Wirt
Kaninchen
43
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
3
3
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
37
23
6
3
3
2
1
1
Optionen
Immunogen Recombinant protein of human U2AF2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung U2AF2 (U2AF59 Antibody Abstract)
Hintergrund

Synonyms: hU2AF(65),hU2AF65,Splicing factor U2AF 65 kDa subunit,U2 (RNU2) small nuclear RNA auxiliary factor 2,U2 auxiliary factor 65 kDa subunit,U2 small nuclear ribonucleoprotein auxiliary factor (65kD),U2 small nuclear RNA auxiliary factor 2,U2 snRNP auxiliary factor large subunit,U2af2,U2AF2,U2AF65

Background: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

Molekulargewicht

Observed_MW: 115kDa

Calculated_MW: 53kDa

Gen-ID 11338
UniProt P26368
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibody (ABIN6568989) Immunofluorescence analysis of U2OS cells using U2AF2 antibody.
Image no. 2 for anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibody (ABIN6568989) Western blot analysis of extracts of various cell lines, using U2AF2 antibody.
Image no. 3 for anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibody (ABIN6568989) Immunoprecipitation analysis of 200ug extracts of SW620 cells using 1ug U2AF2 antibody.