Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antikörper

Details zu Produkt Nr. ABIN6568972
Target
Reaktivität
Human, Maus, Ratte
108
59
53
18
4
3
2
2
2
1
1
1
Wirt
Kaninchen
84
24
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
12
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
74
32
28
28
23
22
13
8
6
3
3
3
1
Optionen
Immunogen Recombinant protein of human FSCN1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung Fascin (FSCN1 Antibody Abstract)
Hintergrund

Synonyms: 55 kDa actin bundling protein,55 kDa actin-bundling protein,Actin bundling protein,actin bundling protein,55-KD,FAN 1,FAN1,Fascin 1,Fascin actin bundling protein 1,Fascin,Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus),Fascin homolog 1,Fascin,sea urchin,homolog of,1,Fascin1,FLJ38511,FSCN 1,FSCN1,FSCN1,HSN,p55,Singed (Drosophila) like (sea urchin fascin homolog like),Singed drosophila homolog like,Singed like (fascin homolog sea urchin) (Drosophila),Singed like (fascin homolog sea urchin),Singed like protein,Singed,drosophila,homolog of,Singed-like protein,SNL,Strongylocentrotus purpuratus

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Molekulargewicht

Observed_MW: 50kDa, 55kDa

Calculated_MW: 54kDa

Gen-ID 6624
UniProt Q16658
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) antibody (ABIN6568972) Western blot analysis of extracts of various cell lines, using FSCN1 antibody.
Image no. 2 for anti-Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) antibody (ABIN6568972) Immunohistochemistry of paraffin-embedded rat stomach using FSCN1 antibody.