Fascin Antikörper

Produktnummer ABIN6568972

Der Kaninchen Polyklonal Anti-Fascin-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Fascin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Fascin Antikörper (ABIN6568972)

Target: Fascin (FSCN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fascin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Fascin Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human FSCN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Fascin

Target: Fascin (FSCN1)

Andere Bezeichnung: Fascin

Hintergrund:

Synonyms: 55 kDa actin bundling protein,55 kDa actin-bundling protein,Actin bundling protein,actin bundling protein,55-KD,FAN 1,FAN1,Fascin 1,Fascin actin bundling protein 1,Fascin,Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus),Fascin homolog 1,Fascin,sea urchin,homolog of,1,Fascin1,FLJ38511,FSCN 1,FSCN1,FSCN1,HSN,p55,Singed (Drosophila) like (sea urchin fascin homolog like),Singed drosophila homolog like,Singed like (fascin homolog sea urchin) (Drosophila),Singed like (fascin homolog sea urchin),Singed like protein,Singed,drosophila,homolog of,Singed-like protein,SNL,Strongylocentrotus purpuratus

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Molekulargewicht:

Observed_MW: 50kDa, 55kDa

Calculated_MW: 54kDa

Gen-ID: 6624

UniProt: Q16658