Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Antikörper

Details zu Produkt Nr. ABIN6568856
Target
Reaktivität
Human, Maus, Ratte
97
22
17
5
1
Wirt
Kaninchen
73
58
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
15
12
10
6
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
63
56
42
28
23
16
14
8
6
6
4
2
2
1
1
Optionen
Immunogen Recombinant protein of human CEACAM1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CEACAM1 (CEACAM1 Antibody Abstract)
Hintergrund

Synonyms: Antigen CD66,BGP 1,BGP,BGP-1,BGPI,Biliary glycoprotein 1,Biliary glycoprotein adhesion molecule,Biliary glycoprotein,Carcinoembryonic antigen related cell adhesion molecule 1,carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein),Carcinoembryonic antigen-related cell adhesion molecule 1,CD66a,CD66a antigen,CEACAM1,CEAM1,meconium antigen 100

Background: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Molekulargewicht

Observed_MW: 120-130kDa

Calculated_MW: 27kDa/35-57kDa

Gen-ID 634
UniProt P13688
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) antibody (ABIN6568856) Western blot analysis of extracts of various cell lines, using CEACAM1 antibody.