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KIR2DL3 Antikörper

KIR2DL3 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6568854
  • Target Alle KIR2DL3 Antikörper anzeigen
    KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
    Reaktivität
    • 53
    • 1
    • 1
    Human, Maus
    Wirt
    • 39
    • 14
    Kaninchen
    Klonalität
    • 40
    • 13
    Polyklonal
    Konjugat
    • 22
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIR2DL3 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 14
    • 14
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human KIR2DL3 (NP_056952.2).
    Isotyp
    IgG
    Top Product
    Discover our top product KIR2DL3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
    Andere Bezeichnung
    KIR2DL3 (KIR2DL3 Produkte)
    Synonyme
    CD158B2 antikoerper, CD158b antikoerper, GL183 antikoerper, KIR-023GB antikoerper, KIR-K7b antikoerper, KIR-K7c antikoerper, KIRCL23 antikoerper, NKAT antikoerper, NKAT2 antikoerper, NKAT2A antikoerper, NKAT2B antikoerper, p58 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 antikoerper, KIR2DL3 antikoerper
    Hintergrund
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Molekulargewicht

    Observed_MW: 45kDa

    Calculated_MW: 27kDa/37kDa

    Gen-ID
    3804
    UniProt
    P43628
    Pathways
    Cancer Immune Checkpoints
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