UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) Antikörper

Details zu Produkt Nr. ABIN6568835
Target
Reaktivität
Human, Maus, Ratte
53
23
22
1
1
1
Wirt
Kaninchen
32
21
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
21
17
16
13
9
8
5
3
1
1
Optionen
Immunogen Recombinant protein of human UGT1A9
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung UGT1A9 (UGT1A9 Antibody Abstract)
Hintergrund

Synonyms: GNT1,HLUGP4,lugP4,UD19,UDP glucuronosyltransferase 1A9,UDP glucuronosyltransferase family 1 member A9,UDP-glucuronosyltransferase 1 family, polypeptide A9,UDP-glucuronosyltransferase 1-9,UDP-glucuronosyltransferase 1-I,UDP-glucuronosyltransferase 1A9,UDPGT 1-9,UDPGT,UGT-1I,UGT1*9,UGT1-09,UGT1.9,Ugt1a9,UGT1A9S,UGT1AI,UGT1I

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.

Molekulargewicht

Observed_MW: 71kDa

Calculated_MW: 49kDa/59kDa

Gen-ID 54600
UniProt O60656
Pathways Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) antibody (ABIN6568835) Western blot analysis of extracts of various cell lines, using UGT1A9 antibody.
Image no. 2 for anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) antibody (ABIN6568835) Immunohistochemistry of paraffin-embedded human liver cancer using UGT1A9 antibody.
Image no. 3 for anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) antibody (ABIN6568835) Immunofluorescence analysis of MCF-7 cells using UGT1A9 antibody.