Replication Factor C (Activator 1) 1, 145kDa (RFC1) Antikörper

Details zu Produkt Nr. ABIN6568811
Target
Reaktivität
Human
59
32
31
4
4
3
3
3
1
Wirt
Kaninchen
54
4
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
42
24
13
8
6
2
1
1
1
Optionen
Immunogen Recombinant protein of human RFC1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RFC1 (RFC1 Antibody Abstract)
Hintergrund

Synonyms: A1 140 kDa subunit,A1,A1 P145 Activator 1 large subunit,Activator 1 140 kDa subunit,Activator 1 large subunit,Activator 1 subunit 1,DNA binding Protein PO GA,DNA-binding protein PO-GA,MHC binding factor beta,MHCBFB,PO GA,RECC1,Replication factor C (activator 1) 1,145  kDa,Replication factor C 140 kDa subunit,Replication factor C,Replication factor C large subunit,Replication factor C subunit 1,Replication factor C1,RF-C 140 kDa subunit,RFC,RFC1,RFC1,RFC140,RFC140 Replication Factor C 140 kDa subunit

Background: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molekulargewicht

Observed_MW: 130kDa

Calculated_MW: 128kDa

Gen-ID 5981
UniProt P35251
Pathways Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) antibody (ABIN6568811) Immunofluorescence analysis of A549 cells using RFC1 antibody.
Image no. 2 for anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) antibody (ABIN6568811) Western blot analysis of extracts of MCF-7 cells, using RFC1 antibody.
Image no. 3 for anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) antibody (ABIN6568811) Immunofluorescence analysis of MCF-7 cells using RFC1 antibody.