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Hydroxysteroid (11-Beta) Dehydrogenase 1a (HSD11B1A) Antikörper Primary Antibody

HSD11B1A Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal
Produktnummer ABIN6568805
$438.90
Zzgl. Versandkosten $45.00
200 μL ABIN6568805
200 μL ABIN6568805
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 12 bis 14 Werktagen
  • Target
    Reaktivität
    Human, Maus
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human HSD11B1
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Andere Bezeichnung
    HSD11 beta
    Hintergrund

    Synonyms: 11 beta HSD 1,11 beta HSD1,11 beta hydroxysteroid dehydrogenase 1,11 DH,11-beta hydroxysteroid dehydrogenase,type 1,11-beta-HSD1,11-beta-hydroxysteroid dehydrogenase 1,11-DH,11DH,Corticosteroid 11 beta dehydrogenase isozyme 1,Corticosteroid 11-beta-dehydrogenase isozyme 1,CORTRD2,DHI1,HDL,HSD 11,HSD11,HSD11B,HSD11B1,HSD11L,Hydroxysteroid (11 beta) dehydrogenase,Hydroxysteroid (11 beta) dehydrogenase 1,MGC13539,SDR26C1,short chain dehydrogenase/reductase family 26C,member 1

    Background: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

    Molekulargewicht

    Observed_MW: 32kDa

    Calculated_MW: 32kDa

    Gen-ID
    3290
    UniProt
    P28845
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