HSD11B1 Produkte
(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
Kategorien
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Ausgewählte HSD11B1 Kategorien
HSD11B1 Antikörper
High quality antibodies with extensive validation data.
HSD11B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSD11B1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HSD11B1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN3181414
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Horse, Human, Mouse, Rat
Applikation
ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN750913
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Applikation
WB, IHC
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN2773867
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HSD11B1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6956632
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6956634
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967494
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HSD11B1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123384
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307101
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3079023
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HSD11B1 Produkten
: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." in: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).: "Synthesis of the N-methyl Derivatives of 2-Aminothiazol-4(5H)-one and Their Interactions with 11βHSD1-Molecular Modeling and in Vitro Studies." in: Chemistry & biodiversity, Vol. 16, Issue 6, pp. e1900065, (2019) (PubMed).
: "A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1." in: Bioorganic chemistry, Vol. 79, pp. 115-121, (2019) (PubMed).
: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).
: "Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis." in: Molecules (Basel, Switzerland), Vol. 21, Issue 11, (2016) (PubMed).
: "Anti-Inflammatory Property of Plantago major Leaf Extract Reduces the Inflammatory Reaction in Experimental Acetaminophen-Induced Liver Injury." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 347861, (2015) (PubMed).
: "A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11?-hydroxysteroid dehydrogenase-1 expression in the offspring." in: PLoS ONE, Vol. 9, Issue 1, pp. e84125, (2014) (PubMed).
: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).
Synonyme und alternative Namen zu HSD11B1
hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1), hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b), hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L), hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), 11-beta-HSD1, 11-DH, CORTRD2, HDL, HSD11, hsd11, HSD11B, hsd11b, HSD11L, LRRGT00065, SDR26C1Bezeichner auf Proteinebene für HSD11B1
- 11-beta-hydroxysteroid dehydrogenase 1
- hydroxysteroid 11-beta dehydrogenase 1
- hydroxysteroid (11-beta) dehydrogenase 1
- corticosteroid 11-beta-dehydrogenase isozyme 1
- short chain dehydrogenase/reductase family 26C, member 1
- 11-DH
- 11-beta-HSD1
- 11-beta-hydroxysteroid dehydrogenase type 1
- 11-beta hydroxysteroid dehydrogenase
- 11 beta-hydroxysteroid dehydrogenase type 1
- 7-alpha-HCD
- 7-alpha-hydroxycholesterol dehydrogenase
- 11beta-HSD-1
- 11beta-HSD1A
- 11beta-hydroxysteroid dehydrogenase type 1
- Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A)
- cortocosteroid 11-beta dehydrogenase
- hydroxysteroid dehydrogenase, 11 beta type 1
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