N-terminal Asparagine Amidase (NTAN1) Antikörper

Details zu Produkt Nr. ABIN6568757
Target
Reaktivität
Human, Maus, Ratte
25
8
Wirt
Kaninchen
24
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Western Blotting (WB)
21
16
3
1
1
Optionen
Immunogen Recombinant protein of human NTAN1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung NTAN1 (NTAN1 Antibody Abstract)
Hintergrund

Synonyms: N terminal Asn amidase,N terminal asparagine amidase ,N terminal asparagine amidohydrolase,NTN-amidase,PNAA ,PNAD ,Protein N-terminal Asn amidase,Protein N-terminal asparagine amidase,Protein N-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase

Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Molekulargewicht

Observed_MW: 35kDa

Calculated_MW: 34kDa

Gen-ID 123803
UniProt Q96AB6
Applikations-hinweise WB 1:200 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-N-terminal Asparagine Amidase (NTAN1) antibody (ABIN6568757) Western blot analysis of extracts of various cell lines, using NTAN1 antibody.