NTAN1 Antikörper

Produktnummer ABIN6568757

Der Kaninchen Polyklonal Anti-NTAN1-Antikörper wurde für WB validiert. Er ist geeignet, NTAN1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für NTAN1 Antikörper (ABIN6568757)

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NTAN1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NTAN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NTAN1

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Andere Bezeichnung: NTAN1

Hintergrund:

Synonyms: N terminal Asn amidase,N terminal asparagine amidase ,N terminal asparagine amidohydrolase,NTN-amidase,PNAA ,PNAD ,Protein N-terminal Asn amidase,Protein N-terminal asparagine amidase,Protein N-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase

Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Molekulargewicht:

Observed_MW: 35kDa

Calculated_MW: 34kDa

Gen-ID: 123803

UniProt: Q96AB6