C9ORF72 Antikörper (C-Term)
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- Target Alle C9ORF72 Antikörper anzeigen
- C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))
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Bindungsspezifität
- AA 396-424, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C9ORF72 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This C9orf72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-424 amino acids from the C-terminal region of human C9orf72.
- Klon
- RB27382
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product C9ORF72 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- C9orf72 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies." in: Amyotrophic lateral sclerosis & frontotemporal degeneration, Vol. 19, Issue 1-2, pp. 102-111, (2018) (PubMed).
: "The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 51, (2017) (PubMed).
: "Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease." in: Science translational medicine, Vol. 8, Issue 347, pp. 347ra93, (2017) (PubMed).
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Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies." in: Amyotrophic lateral sclerosis & frontotemporal degeneration, Vol. 19, Issue 1-2, pp. 102-111, (2018) (PubMed).
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- Target
- C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))
- Andere Bezeichnung
- C9orf72 (C9ORF72 Produkte)
- Molekulargewicht
- 54328
- Gen-ID
- 203228
- NCBI Accession
- NP_001242983, NP_060795, NP_659442
- UniProt
- Q96LT7
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