POT1 Antikörper (Protection of Telomeres 1 Homolog (S. Pombe))

Details for Product anti-POT1 Antibody No. ABIN6568518
Target
Reaktivität
Human, Maus, Ratte
32
5
3
3
2
2
2
2
2
1
1
Wirt
Kaninchen
30
2
Klonalität
Polyklonal
Konjugat
Dieser POT1 Antikörper ist unkonjugiert
2
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
22
13
5
2
2
2
1
1
Optionen
Immunogen Recombinant protein of human POT1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung POT1 (POT1 Antibody Abstract)
Hintergrund

Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1

Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Molekulargewicht

Observed_MW: 75kDa

Calculated_MW: 60kDa/71kDa

Gen-ID 25913
UniProt Q9NUX5
Pathways Zellzyklus, Telomere Maintenance
Applikations-hinweise WB 1:200 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Protection of Telomeres 1 Homolog (S. Pombe) (POT1) antibody (ABIN6568518) Western blot analysis of extracts of various cell lines, using POT1 antibody.
Image no. 2 for anti-Protection of Telomeres 1 Homolog (S. Pombe) (POT1) antibody (ABIN6568518) Immunohistochemistry of paraffin-embedded rat kidney using POT1 antibody.
Image no. 3 for anti-Protection of Telomeres 1 Homolog (S. Pombe) (POT1) antibody (ABIN6568518) Immunohistochemistry of paraffin-embedded mouse lung using POT1 antibody.