POT1 Antikörper
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- Target Alle POT1 Antikörper anzeigen
- POT1 (Protection of Telomeres 1 (POT1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human POT1
- Isotyp
- IgG
- Top Product
- Discover our top product POT1 Primärantikörper
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- Applikationshinweise
- WB 1:200 - 1:2000 IHC 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- POT1 (Protection of Telomeres 1 (POT1))
- Andere Bezeichnung
- POT1 (POT1 Produkte)
- Hintergrund
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Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1
Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
- Molekulargewicht
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Observed_MW: 75kDa
Calculated_MW: 60kDa/71kDa
- Gen-ID
- 25913
- UniProt
- Q9NUX5
- Pathways
- Zellzyklus, Telomere Maintenance
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